I love artsy minimalist boxes. The Grand Theft Auto series post-3 are eyecatching and interesting (and thank god Rockstar's artists got better at drawing people with Vice City onward), and then there's stuff like the Japanese ICO box.
But right now, my personal favorite is the box of Heretic: Shadow of the Serpent Riders:
The entire box is designed to look like the in-game Tome of Power items, complete with fake spine bindings on the sides.
Much of that old-Hollywood style handrawn art (think the old James Bond posters) is so much better that the 3-D clip art often seen today. The art-deco look such as that which Descent sports os also very appealing much of the time. Minimalism in that sense can be very artistic when approached from the right vantage.